no do not do that.. do so will excessively dry out your skin.. just use the differin gel and a moisturizer.. if needed then put proactive on as a spot treatment on each individual blemish.. but just try the differin gel out alone for about 2-3 weeks.. it takes a while for new skin care products to work so be patient with it.. differin is a great topical cream im sure you with be very happy with the results
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